Endocrine Abstracts

The Indian Medical Practitioners Expressions Regarding Drug Interventions in All Aspects of Metabolic Syndrome (IMPERIAL) study-5 was planned to assess physicians’ perceptions regarding the relative importance and effectiveness of various methods used to upgrade or intensify insulin therapy in patients not achieving glycemic control.Seventy-four diabetologists/endocrinologists, with clinical experience of 20.25±5.0 years, attending a conference...

Objective: The aim of this exploratory study was to assess the effect of growth hormone on semen parameters in men with primary infertility and normogonadotropic idiopathic oligoasthenospermia.Method: This study was performed as a prospective, open- label, non-randomized observational study in a private practice in fourteen men, aged 26 to 35, with normogonadotropic idiopathic oligoasthenospermia. Growth hormone 1.5 IU/day was administered for 6 months a...

This study was designed as a retrospective multicentric study to assess the efficacy of various methods of effective intensification and optimization of premixed insulin analogue therapy. 200 consecutive OPD charts of patients poorly controlled on premixed insulin twice daily were reviewed for changes advised by the treating physician. Data was assessed for cues, methods and efficacy of intensification of therapy.A casual blood glucose value >250 mg%...

Objective: Premixed aspart is being used in once, twice and thrice-daily regimes in persons with diabetes. This study was designed as a cross-sectional, observational study to assess the need for three-dose premixed aspart in different subsets of subjects with type 1 and type 2 diabetes attending an endocrine OPD.Methods: Records of 200 consecutive patients receiving premixed insulin were assessed to determine the frequency of insulin dosage and its clin...

Diabetes is endemic in society. Beyond lifestyle modification (often short lived) and metformin, which while effective has gastrointestinal side effects, other available pharmacological options are challenging to implement across populations of newly diagnosed patients. The recent position statement by ADA/EASD calls for patient-centred individualised therapies to suit patients’ need. Glucose-lowering nutritional supplements may be an effective and safe option for newly d...

This paper studies the attitudes of postgraduate medical students towards endocrinology and diabetology as a career.Fifty post graduate students, pursuing residency in internal medicine, at various colleges throughout India, were requested to fill up a pre-tested, five point Likert scale questionnaire designed to assess their likings for various branches and aspects of medicine.The average age of the respondents was 27 years, with ...

This multicentric, observational, non interventional study of patients with type 1 diabetes observed their knowledge, attitudes and practices regarding complementary and alternative medicine (CAM), including nutraceuticals. One hundred and thirty-five subjects with type 1 diabetes, aged <20 years, and their parents were surveyed using a structured pre-tested questionnaire.The cohort included 65.92% boys, 37.04% rural dwellers and 31.85% patients with...

Objective: IMPROVE study was designed to assess the safety and effectiveness of NovoMix30® in type 2 diabetes subjects under normal clinical practice conditions.Methods: This large multi-national, open label, prospective, 6 month long observational study captured data for above 50 000 patients started on NovoMix30® with/without oral anti-diabetic drugs (OADs)/other insulin. This paper analyses safety data of 17 995 patient...

Introduction: Although alpha-glucosidase inhibitors (aGIs), including acarbose, are recommended in several international guidelines, they are not widely used worldwide due to a perception that they are less effective in Caucasians than Asians. A study was undertaken to investigate whether differences between ethnicity/region populations exist.Methods/design: We pooled data from 10 non-interventional and post-marketing studies from 21 countries, provinces...

BackgroundApart from long-term complications associated with diabetes(T2DM), the psychological impact also significantly contributes to poor outcomes in persons living with diabetes. An observational survey was undertaken to assess various physician-related factors that can help define “glycemic happiness” for persons living with T2DM.MethodsA prospective, multicentric, cross sectional, observationa...